DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...

If all the DNA in a human cell was stretched out end to end, it would be roughly six feet long. That’s a lot of genetic information to pack into a cell that is, on average, one-fifth the size of a ...

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

The upper right portion illustrates viral nucleosome-like particles formed by co-occurring viral histone triplets and singlets. On the lower right, a network depicts distinct types of viral ...

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers-about a millionth of a milliliter. The cell manages this by ...

Discovering How DNA Reaches Its Most Compact Form For many years, researchers did not know how this extra level of chromatin compaction occurred. In 2019, HHMI Investigator Michael Rosen and his team ...

Six feet of DNA crammed into a cell nucleus narrower than a human hair: Life may pack no tighter puzzle than this. And yet, biology pulls it off every second, compressing genetic material with a ...