Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...
Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...
In a new study, scientists at the Max Planck Institute for Evolutionary Anthropology in Leipzig analyzed the impact of more ...
A new study from the Max Planck Institute for Evolutionary Anthropology examined how > 2,000 clinically approved drugs affect ...
A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...
New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...
Large-scale drug atlas uncovers new genome editing modulators and potential therapeutic strategies for DNA repair-deficient cancers ...
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Hidden DNA weak spot near gene start mutates rapidly

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...
To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most ...