This figure illustrates three key applications of AI in antimicrobial drug development: (1) target identification and validation, including novel target discovery, affinity prediction, multi-target ...

“The public outcome of compound claim cases indicates that the success rate is much lower when compared with challenges of other types of claims.” Patent challenges are an indispensable part of the ...

The identification of promising lead compounds from high-throughput screens is still a very complex problem. A new high-throughput assay for identifying aggregation-based false positives could help.

Scientists Seek to Develop New and Better Ways to Look at Existing Data At CHI’s “World Pharmaceutical Congress” held recently in Philadelphia, there was no shortage of good ideas for ways to optimize ...

Lead optimization aims at enhancing the most promising compounds to improve effectiveness, diminish toxicity, or increase absorption. Many of the technologies for lead discovery overlap with lead ...

“Selection of an “acceptable” lead is probably the most important governing factor in compound claim challenges, with the potential to make or break the case.” In an earlier article, “Tips for ...

A client of Concept Life Sciences had discovered a series of innovative peptides with strong phenotypic potency. However, progress was hindered by a lack of target engagement data, which limited the ...