This study is led by Dr. Yue Zhou (State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, ...

A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.

Within the realm of genetic regulation, chromatin modifications such as histone methylation and acetylation play pivotal roles in the transcriptional control of genes. Disruptions in these processes ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...

If I asked you, dear reader, to come up with a shortlist of the most monumental scientific achievements of the last century, chances are the Human Genome Project (HGP) would appear somewhere on that ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...