This study introduces TEAM (Targeted Elimination and Microcell-Mediated Transfer), a novel programmable platform that enables ...

Since the 1800s, scientists have noted configuration of centromeres, a special chromosomal region that is vital for cell division, in the nucleus. Up until this point, however, the determining ...

About a third to two-thirds down the shaft of a chromosome is a constricted site called the centromere. When a chromosome replicates, the old and new pair (called chromatids) are held together at this ...

Centromeres are curious structures. These specially organized chromosomal regions are best known for their unique and critical role in cell division, in which they are well understood to serve as the ...

Researchers at Osaka University say they have clarified the structure of the centromeric region in chicken cells using cryogenic electron microscopy (cryo-EM). The team published its study in “The ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...

Centromeres are the chromosomal domains at which the kinetochore, a protein complex required for the correct separation of chromosomes during mitosis and meiosis, is assembled. The incorporation of ...

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.