Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

IN his presidential address to the Royal Microscopical Society delivered on Jan. 20, Prof. R. Ruggles Gates reviewed present knowledge regarding nuclear structure, especially in relation to genetics.

A hidden structure inside the cell is rewriting how scientists understand leukemia. Beneath the microscope, what looked like ...

Cellular mechanical states modulate cytoskeleton–nucleus links and trigger the translocation of regulatory molecules to the nucleus. The remodelling of cytoskeleton–nucleus links results in distinct ...

The Kanazawa team led by Katsuya Sakai, discovered that CHD1 uses a flexible region to form tiny liquid-like droplets, called condensates, that act as hubs for controlling the activity of crucial ...

Nucleome is backed by a world-class syndicate of investors: M Ventures, the venture capital arm of Merck KGaA; Johnson and Johnson Innovation - JJDC, Inc. ("JJDC"); Pfizer Ventures; British Business ...

Researchers from Skoltech, the University of Potsdam, and the Massachusetts Institute of Technology have discovered a ...

Kaitlin McCreery is the coauthor of a new paper published in Small that deals with diagnosing diseases such as osteoarthritis in soft tissue. McCreery is currently a PhD student in the Neu Lab where ...

Kanazawa University, report in ACS Applied Nano Materials a new method to precisely measure nuclear elasticity—the stiffness ...

After uncovering the structure of a protein that allows respiratory syncytial virus (RSV) to skirt the immune response in a 2017 study, a team of researchers at Washington University in St. Louis went ...

A copy of your DNA is harbored in the nuclei of all 37.2 trillion of your cells. Theoretically, all of these cells have the same capabilities, because they carry the same blueprint. So how does your ...