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Cleavage of cohesins and cyclin-dependent kinase (CDK) inhibition are thought to be sufficient for triggering chromosome segregation. Here we identify an essential requirement for anaphase chromosome ...

Blocking certain enzymes in the cell may prevent cancer cell division and growth, according to new findings. Blocking certain enzymes in the cell may prevent cancer cell division and growth, according ...

In a major advance for molecular biology and cancer research, scientists have uncovered the molecular mechanisms that control a key step during the activation of cyclin-dependent kinases (CDKs) – the ...