The clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated proteins (Cas) system is a bacterial defense mechanism that uses RNA-guided enzymes to cut specific sequences ...

Scientists have developed ThermoCas9, a CRISPR enzyme capable of distinguishing cancer cells from healthy ones by reading DNA methylation patterns, potentially reducing off-target edits. In lab tests, ...

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling ...

Sidra Medicine launches Casgevy in Qatar, the first CRISPR gene therapy for sickle cell and thalassemia, offering a potential ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...

In December 2020, the New England Journal of Medicine published a paper titled CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia, marking an exciting new chapter in the treatment of ...

MaxCyte’s Flow Electroporation technology delivers CRISPR/Cas-9 gene-editing tools to a patient’s T cells. The technology uses electrical pulses to create temporary pores in the cell membrane, which ...

Gene editing in plants remains challenging, with the traditional non-homologous end-joining (cNHEJ) repair pathway often hindering precision. In this study, researchers advanced CRISPR-Cas-based gene ...

The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to protect ...

High School Insider is a user-generated content website that enables high school students to post their stories and report on issues that matter to them and their communities.