The blood–brain barrier (BBB) is meant to protect the brain ... particles that have a diameter of several nanometers can also cross the BBB by carrier-mediated transport. Although very small ...

The research team designed and tested a library of lipids to optimize their ability to cross the blood-brain barrier. Through ...

Delivering anything therapeutic to the brain has long been a challenge, largely due to the blood-brain barrier, a layer of cells that separates the vessels that supply the brain with blood from the ...

Vect-Horus has a clinical-phase solution to a key drug development challenge: crossing the blood–brain barrier (BBB ... that other companies use to cross the BBB. The weight difference ...

Overall, we accounted for more than 95% of the variability in the data from drugs that cross the blood-brain barrier by passive diffusion." The study also looked at those compounds that do not go ...

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions ...

Researchers have developed a personalized blood test that may offer a faster, less invasive way to track high-grade glioma progression.

Furthermore, docetaxel (the drug of choice for the first-line treatment of castration-resistant PC) cannot cross the blood–brain barrier and control metastatic foci. However, this problem may be ...

The properties of the blood-brain barrier serve a vital protective role, but they also keep drugs from reaching the organ. Big pharmaceutical companies have been making deals for technologies that ...

The blood-brain barrier is a selectively permeable barrier that protects the brain from pathogens, cancer cells and other dangers. When healthy, the BBB only allows an elite group of molecules in ...

Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...