The reaction (a ruthenium-catalysed olefin metathesis) essentially stabilizes the helical conformation of the BH3 mimics, referred to as stabilized α-helix of BCL2 domains (SAHBs). Insertion of ...

Discover how dynamic BH3 profiling can predict responses in lung cancer patients to ALK inhibitors, enhancing personalized ...

A research team from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences uncovered that syn-CH3CHOO's ...