Universal CAR T cells produce rapid remissions and enable allogeneic stem cell transplants in patients with relapsed or refractory T-cell acute lymphoblastic leukemia.
A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in ...
Explore how engineered extracellular vesicles can enhance antigen-specific regulatory T cells to improve immune response.
Engineered dendritic cells capture tumor EVs, enhancing antigen presentation and T cell activation to boost cancer immunotherapy in preclinical models.
Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...
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Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has ...
A single signaling pathway controls whether immune cells attack or befriend cells they encounter while patrolling our bodies, researchers at Stanford Medicine have found. Manipulating this pathway ...
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New findings show why the human intestine uniquely presents gluten to T cells
Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity ...
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