Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of ...

which also affects the arm and hand functions). A total of 78 people were treated with the antibody that was injected directly into the spinal canal; the remaining 48 people received placebo.

An investigational monoclonal antibody called bentracimab can safely and effectively reverse potentially catastrophic bleeding complications linked to ticagrelor, a common drug used to treat patients ...

Antibodies that interfere with IL-6 function Tocilizumab is a monoclonal antibody directed against the IL-6 receptor that has established benefit in RA both with regards to clinical efficacy and ...

Many proteins group together in what are called protein complexes to carry out biological functions. The traditional method of generating antibodies by immunizing animals struggles to make ...

There are many immunological diseases related to antibody functions and production of autoimmune antibodies and it is essential that their treatments be continued during pregnancy. The aim of the ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

Significantly, all of the autoantibodies directly disrupted the receptor's function as an ion channel. The findings challenge previous assumptions about how myasthenia gravis antibodies disrupt ...

With respect to humanization, Fusion Antibodies utilizes an in-silico library of mature human frameworks to deliver diverse humanized variants that retain function and maintain an affinity within ...

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...