The symptoms of hyperkalemia begin with muscle weakness. As serum potassium levels rise, symptoms progress to more significant muscle twitching, weakness, nausea, and cramping. [69] Cardiac conduction ...
It's long been known that use of a renin-angiotensin-aldosterone system (RAAS) antagonist slows the progression of kidney disease and specifically slows progression of advanced kidney disease, ...
Please provide your email address to receive an email when new articles are posted on . After a hyperkalemia event, mineralocorticoid receptor antagonists were discontinued in up to 46% of patients.
Mineralys' lorundrostat, a selective aldosterone synthase inhibitor, shows promise in treating resistant hypertension with fewer side effects compared to current MRAs. Upcoming catalysts include ...
Among selected people with uncontrolled hypertension, blood pressure (BP) could be successfully reduced with a highly selective aldosterone synthase inhibitor, a phase II dose-finding trial found. In ...
Please provide your email address to receive an email when new articles are posted on . An updated clinical practice guideline suggested screening all people with hypertension for primary ...
When ordering renin-to-aldosterone ratios in the workup of secondary hypertension, how does one deal with the severe hypertension that results when the patient discontinues both ACE inhibitors and ...
An investigational antihypertensive agent that inhibits the enzyme involved in aldosterone production, called MLS-101, significantly reduces blood pressure in patients with uncontrolled and resistant ...