During a discussion on the next frontier of medicine for cold agglutinin disease, stakeholders react to the rationale for studying newer, novel complement-targeted therapies. Neil Minkoff, MD: Let me ...

Sutimlimab is an IgG4 monoclonal antibody that inhibits the classical complement pathway. The Food and Drug Administration (FDA) has approved Enjaymo™ (sutimlimab-jome) to decrease the need for red ...

Diagnostic criteria used by health care professionals who manage patients with autoimmune hemolytic anemias to help distinguish cold agglutinin disease from other medical conditions. Jeremy Lorber, MD ...

Please provide your email address to receive an email when new articles are posted on . Research presented at ASH Annual Meeting and Exposition provided an exciting update on many of the ...

Cold agglutinin disease (CAD) is a rare subtype of autoimmune haemolytic anaemia (AIHA) where autoantibodies, predominantly of the IgM class, bind to red blood cells at reduced temperatures. This ...

Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia — a condition in which you have inadequate red blood cells due to premature destruction of those cells by your own immune ...

In a recent case report published in the Journal of Clinical Laboratory Analysis, researchers presented two cases to highlight the impact of cold agglutinin syndrome (CAS) on clinical presentations in ...

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Dear P.W.: Cold agglutinin disease is a specific type of anemia where antibodies attack and destroy a person’s own red blood cells. Unlike the usual type of autoimmune hemolytic (”hemolytic” means ...

Anemia caused by the autoimmune disorder cold agglutin disease now has its first approved treatment, a Sanofi drug designed to block a pathway key to the progression of this condition. The FDA’s ...

3D rendering Microscopic illustration of red blood cell background Researchers sought to determine whether sutimlimab would be safe and effective in treating patients with cold agglutinin disease. The ...

Livedo is a cutaneous cyanotic sign characterized by a net-like discoloration, and has two different forms. Livedo reticularis, which usually appears on the legs, is a primary or physiological ...