Samuel has been a versatile piece for the 49ers since his arrival in 2019 as a second-round pick. In 81 games for San Francisco, he's tallied 5,935 scrimmage yards and has been a pivotal for the 49ers ...

The Arizona Cardinals have one final game left this season, closing it out at home against the San Francisco 49ers. Kickoff from State Farm Stadium is at 4:25 p.m. ET (2:25 p.m. Arizona time ...

The 49ers granted Samuel and his agent permission to seek a trade once this latest request came a month ago, when Samuel, 29, ...

For coach Jonathan Gannon and QB Kyler Murray, ending the season with a win will give Arizona a confidence boost heading into the offseason.

The Arizona Cardinals will host the San Francisco 49ers at State Farm Stadium in Glendale, Arizona, on Sunday, January 5, at 1:25 p.m. PT. The Cardinals are currently favored by 4.5 points.

How do all 32 teams in the NFL stack up against each other going into the 2025 NFL offseason? Here's breaking down who's ...

TV: FOX. Radio: 98.7 FM. Last time they played: The 49ers made easy work of the Cardinals in a 45-29 win last December. That defeat is the most points the Cardinals have allowed in a game since 2016.

The San Francisco 49ers are preparing for their Week 18 contest against the Arizona Cardinals on Sunday at State Farm Stadium in Glendale, Arizona. Several key players were absent from the second ...

James Conner will not play in the Arizona Cardinals’ season finale against the San Francisco 49ers. He was placed on injured reserve earlier this week, ending his season. Several other Cardinals ...

Following a narrow 40-34 home loss to the Detroit Lions on "Monday Night Football," the 6-10 49ers conclude the season against the 7-9 Arizona Cardinals on Sunday at State Farm Stadium.

Discussing the 49ers preparations for their 2024 season finale against the Arizona Cardinals, including quarterback changes, players to watch and the importance of finishing the season strong with ...