The game ended on PSU veteran quarterback Drew Allar’s interception on a first-down play from the Ducks’ 25. Allar tried to hit tight end Luke Reynolds on the right side on a boundary throw that talented Oregon safety Dillon Thieneman appeared to be waiting on. The Ducks’ DB caught the ball at the 17, securing Oregon’s upset.

Big Ten foes match up when the No. 6 Penn State Nittany Lions (3-1) and the UCLA Bruins (0-4) square off on Saturday, October 4, 2025 at the Rose Bowl. For our pick on which team will come out on top, keep scrolling.

College football Week 6 odds, picks, predictions, TV channel, streaming for Penn State Nittany Lions vs UCLA Bruins game on Saturday, Oct. 4, 2025.

UCLA is in transition after firing coach DeShaun Foster in Week 3 following a winless start to 2025. Interim coach Tim Skipper is tasked with steadying the Bruins while the program searches for a permanent replacement. The last time UCLA beat Penn State was 1967.

Going into their Week 5 matchup against the Wildcats, UCLA's remaining strength of schedule ranked 11th in all of college football, according to ESPN's Football Power Index (FPI). Northwestern came into the season as one of the worst teams in the Big Ten.

Penn State will travel to UCLA for a showdown in the Big Ten during Week 6. The Nittany Lions won last year’s matchup 27-11 during the Bruins’ first season in the conference.

Penn State kicks off at 3:30 p.m. on CBS at UCLA this week, while Northwestern goes at 3:30 p.m. on Big Ten Network against Louisiana-Monroe. Penn State and Northwestern have not played since 2023, when the Lions won 41-13 on the road.

A key Big Ten matchup takes place Sunday as UCLA travels to face No. 15 Penn State in women’s volleyball. Both teams sit at 6-4 and are looking to climb in the conference standings.