Leslie Charleson, known for her role as Monica Quartermaine on “General Hospital,” has died. She was 79. Executive producer Frank Valentini announced Charleson’s death Sunday on the show’s Instagram page.

Ms. Charleson played Dr. Monica Quartermaine, a cardiologist and family matriarch, on the daytime series for 46 years.

The fictional character Monica Quartermaine was introduced in 1976 and quickly became one of the show’s most iconic and enduring figures.