Wilkesboro is an unincorporated community in Washington County, Oregon, United States. It is located on Oregon Route 6, one mile east of Banks. Wilkesboro was settled in 1845 by its namesake Peyton G. Wilkes, and platted in 1912. The locale was named about the time United Railways built its interurban line through the area. The post office was establis…Wilkesboro is an unincorporated community in Washington County, Oregon, United States. It is located on Oregon Route 6, one mile east of Banks. Wilkesboro was settled in 1845 by its namesake Peyton G. Wilkes, and platted in 1912. The locale was named about the time United Railways built its interurban line through the area. The post office was established in 1916. In 1915 the town had a population of 50, two churches, a fraternal lodge, a farmer's alliance and a railroad depot. Later there was also a grocery, meat market, blacksmith shop and brickyard, but by 1990 none of these businesses remained. The post office was closed in 1932.